Abuse of Letrozole

If you are planning to use Letrozole (Femara) as an oral non-steroidal aromatase inhibitor immediately after or at the end of an anabolic steroid cycle, it is important for you to have a clear understanding and tips on how to use Letrozole.

Use of Letrozole is not advised to pregnant and breastfeeding women and children or those having allergies to the drug or any of its ingredients or those treated for high blood pressure, liver damage, stroke, and kidney damage or making use of drugs like Prasterone, Tamoxifen, DHEA, and Androstenedione. When abused or overdosed, it can cause side effects such as hot flushes, night sweats, vomiting, bone pain, loss of appetite, headache, stomach pain, cough, and breast pain; use of the drug is not indicated to those treated for high blood fats (cholesterol), bone problems (such as osteopenia, osteoporosis), stroke or blood clots, heart disease (such as chest pain, heart attack, heart failure), high blood pressure, kidney problems, and liver problems. Abuse of this drug may cause chest/jaw/left arm pain, confusion, coughing up blood, sudden dizziness/fainting, pain/swelling/warmth in the groin/calf, weakness on one side of the body, vision changes, sudden/severe headache, slurred speech, bone fractures, mental/mood changes (such as depression, anxiety), swelling of arms/legs.

Drugs like estrogens (such as ethinyl estradiol, conjugated estrogens), estrogen blockers (such as anastrozole, tamoxifen) may interfere with Letrozole’s functioning and best avoided and Letrozole (Femara) is best stored at a controlled room temperature of 20° to 25°C (68° to 77°F) with excursions permitted to 15° to 30°C (59° to 86°F).